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Congenital Diaphragmatic Hernia

Congenital Diaphragmatic Hernia

Our Mission: CDH International was created to help families of babies born with Congenital Diaphragmatic Hernia by providing support services, promoting research and raising awareness.

Congenital Diaphragmatic Hernia (CDH) is a birth defect that occurs when a baby’s diaphragm (a thin sheet of muscle that separates the abdomen from the chest) fails to fully form, allowing abdominal organs to enter the chest cavity and prevent lung growth.

CDH occurs in approximately 1 in 2500 births, with over 1600 babies diagnosed each year in the United States alone. There is currently no known cause, but studies have suggested that it is likely due to a number of genetic and environmental factors.

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Research: Cyanoacrylate for Safer Mesh Fixation During Laparoscopic Repair of Morgagni Hernia.

Ann Thorac Surg. 2020 Apr;109(4):e305-e307. doi: 10.1016/j.athoracsur.2019.10.019. Epub 2019 Nov 27. https://pmlegacy.ncbi.nlm.nih.gov/pubmed/31785292 Cyanoacrylate for Safer Mesh Fixation During Laparoscopic Repair of Morgagni Hernia. Hoyuela C1, Juvany M2, Guillaumes S2. Author information Abstract The surgical repair of all Morgagni hernias is recommended to avoid the risk of strangulation of hernia contents. Mesh augmentation repair can reduce the risk of recurrence, but severe injuries have …

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Research:Rare Course of Bilateral Congenital Diaphragmatic Hernia Treated Thoracoscopically-Case Report.

Front Pediatr. 2020 Apr 29;8:209. doi: 10.3389/fped.2020.00209. eCollection 2020. https://pmlegacy.ncbi.nlm.nih.gov/pubmed/32411638 Rare Course of Bilateral Congenital Diaphragmatic Hernia Treated Thoracoscopically-Case Report. Toczewski K1, Gerus S1, Palczewski M1, Patkowski D1. Author information Abstract We present a rare case of metachronous bilateral congenital diaphragmatic hernia (CDH) in a newborn with additional malformations: macroglossia, pectus excavatum, and confirmed Simpson-Golabi-Behmel syndrome. We performed a successful thoracoscopic subsequent repair …

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Research: Acute intrathoracic gastric volvulus: A rare delayed presentation of congenital diaphragmatic hernia: A case report.

Int J Surg Case Rep. 2020 May 11;70:123-125. doi: 10.1016/j.ijscr.2020.04.066. [Epub ahead of print] Acute intrathoracic gastric volvulus: A rare delayed presentation of congenital diaphragmatic hernia: A case report. Zain M1, Abada M2, Abouheba M3, Elrouby A4, Ibrahim A5. https://pmlegacy.ncbi.nlm.nih.gov/pubmed/32416482 Author information Abstract INTRODUCTION: Acute intrathoracic gastric volvulus occurs when the stomach undergoes organoaxial rotation in the chest due presence of …

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Research: Treating Center Volume and Congenital Diaphragmatic Hernia Outcomes in California.

J Pediatr. 2020 May 14. pii: S0022-3476(20)30357-7. doi: 10.1016/j.jpeds.2020.03.028. [Epub ahead of print] https://pmlegacy.ncbi.nlm.nih.gov/pubmed/32418817 Treating Center Volume and Congenital Diaphragmatic Hernia Outcomes in California. Apfeld JC1, Kastenberg ZJ2, Gibbons AT3, Carmichael SL4, Lee HC5, Sylvester KG6. Author information Abstract OBJECTIVE: To examined outcomes for infants born with congenital diaphragmatic hernias (CDH), according to specific treatment center volume indicators. STUDY DESIGN: A population-based retrospective cohort study …

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Research: Risk of malformation after ondansetron in pregnancy: An updated systematic review and meta-analysis.

Birth Defects Res. 2020 May 18. doi: 10.1002/bdr2.1705. [Epub ahead of print] https://pmlegacy.ncbi.nlm.nih.gov/pubmed/32420702 Risk of malformation after ondansetron in pregnancy: An updated systematic review and meta-analysis. Picot C1, Berard A1,2, Grenet G1, Ripoche E3, Cucherat M1,4, Cottin J1. Author information Abstract Ondansetron is increasingly used off label to treat nausea and vomiting during pregnancy. The main objective of this study was …

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Research: A Case of Split Notochord Syndrome with Left Congenital Diaphragmatic Hernia: A Rare Association.

J Pediatr Neurosci. 2020 Jan-Mar;15(1):42-44. doi: 10.4103/JPN.JPN_85_19. Epub 2020 Mar 18. A Case of Split Notochord Syndrome with Left Congenital Diaphragmatic Hernia: A Rare Association. Pan P1. https://pmlegacy.ncbi.nlm.nih.gov/pubmed/32435306 Author information Abstract Split notochord syndrome is a rare neural tube malformation involving the brain, spinal cord, and vertebral column. In nearly half of the cases, the malformation also …

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Research: Congenital diaphragmatic hernia presenting with symptoms within the first day of life; outcomes from a non-ECMO centre in Denmark.

BMC Pediatr. 2020 May 7;20(1):196. doi: 10.1186/s12887-020-02072-2. https://www.ncbi.nlm.nih.gov/pubmed/32381070 Congenital diaphragmatic hernia presenting with symptoms within the first day of life; outcomes from a non-ECMO centre in Denmark. Larsen UL1,2, Jepsen S3, Strøm T4, Qvist N5, Toft P4. Author information Abstract BACKGROUND: Between 1998 and 2015, we report on the survival of congenital diaphragmatic hernia (CDH)-infants presenting with symptoms within the first 24 h of …

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Research: Nitric Oxide in Congenital Diaphragmatic Hernia.

Adv Neonatal Care. 2020 May 6. doi: 10.1097/ANC.0000000000000753. [Epub ahead of print] https://www.ncbi.nlm.nih.gov/pubmed/32384329 The Use of Inhaled Nitric Oxide in Congenital Diaphragmatic Hernia. Novotny AM1. Author information Abstract BACKGROUND: Congenital diaphragmatic hernia (CDH) is a complex congenital defect of the diaphragm that allows abdominal contents to herniate into the chest cavity, altering pulmonary development, and leading to pulmonary hypoplasia and …

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Research: Early postnatal changes of circulating N-terminal-pro-B-type natriuretic peptide in neonates with congenital diaphragmatic hernia.

Early Hum Dev. 2020 Apr 25;146:105049. doi: 10.1016/j.earlhumdev.2020.105049. [Epub ahead of print] https://www.ncbi.nlm.nih.gov/pubmed/32402829 Early postnatal changes of circulating N-terminal-pro-B-type natriuretic peptide in neonates with congenital diaphragmatic hernia. Heindel K1, Holdenrieder S2, Patel N3, Bartmann P1, Schroeder L1, Berg C4, Merz WM4, Mueller A1, Kipfmueller F5. Author information Abstract BACKGROUND: Severity of lung hypoplasia, pulmonary hypertension (PH) and cardiac dysfunction are major contributors to mortality in congenital …

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CDH International at the 2020 ECRD Conference

CDH International was proud to present our research poster at 10th European Conference on Rare Disease & Orphan Products in Sweden. Because of the pandemic, the entire conference was virtual and thus allowed us to participate from North Carolina. This is our 3rd year attending the ECRD and we are working hard on building rare …