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What is Congenital Diaphragmatic Hernia?

Congenital Diaphragmatic Hernia (CDH) is a birth defect that occurs when a baby’s diaphragm (a thin sheet of muscle that separates the abdomen from the chest) fails to fully form, allowing abdominal organs to enter the chest cavity and prevent lung growth.

CDH occurs in approximately 1 in 2500 births, with over 1600 babies diagnosed each year in the United States alone. There is currently no known cause, but studies have suggested that it is likely due to a number of genetic and environmental factors.

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Research: Recessive PIGN Mutations in Fryns Syndrome: Evidence for Genetic Heterogeneity.

Hum Mutat. 2016 Jul;37(7):621. doi: 10.1002/humu.23016. https://www.ncbi.nlm.nih.gov/pubmed/27300081 Recessive PIGN Mutations in Fryns Syndrome: Evidence for Genetic Heterogeneity. Thompson MD1, Cole DE2. Author information Comment on Fryns Syndrome Associated with Recessive Mutations in …

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Research: Chest ultrasound for guiding lung recruitment maneuvers.

Med Intensiva. 2018 Nov;42(8):e20. doi: 10.1016/j.medin.2017.07.001. Epub 2017 Aug 30. https://www.ncbi.nlm.nih.gov/pubmed/28869041 Chest ultrasound for guiding lung recruitment maneuvers. [Article in English, Spanish]Del Rey Hurtado de Mendoza B1, Sanchez-de-Toledo J2, Rodríguez-Fanjul J3. Author information …

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Research: Racial and Ethnic Differences in Pediatric Pulmonary Hypertension: An Analysis of the Pediatric Pulmonary Hypertension Network Registry

J Pediatr. 2019 Jun 5. pii: S0022-3476(19)30529-3. doi: 10.1016/j.jpeds.2019.04.046. [Epub ahead of print] Racial and Ethnic Differences in Pediatric Pulmonary Hypertension: An Analysis of the Pediatric Pulmonary Hypertension Network Registry. Ong …

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Research: One-year outcomes for congenital diaphragmatic hernia.

BJS Open. 2019 Jan 31;3(3):305-313. doi: 10.1002/bjs5.50135. eCollection 2019 Jun. https://www.ncbi.nlm.nih.gov/pubmed/31183446 One-year outcomes for congenital diaphragmatic hernia. Wang Y1, Honeyford K1, Aylin P1, Bottle A1, Giuliani S2. Author information Abstract BACKGROUND: Congenital diaphragmatic hernia (CDH) is a congenitalanomaly …

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Research: One-year outcomes for congenital diaphragmatic hernia.

BJS Open. 2019 May 9;3(3):415-416. doi: 10.1002/bjs5.50169. eCollection 2019 Jun. https://www.ncbi.nlm.nih.gov/pubmed/31183457 One-year outcomes for congenital diaphragmatic hernia. Lansdale N1, Wilkinson D1. Author information PMID: 31183457 PMCID: PMC6551398 DOI: 10.1002/bjs5.50169Free PMC Article

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Research: Authors’ reply: One-year outcomes for congenital diaphragmatic hernia

BJS Open. 2019 May 9;3(3):415. doi: 10.1002/bjs5.50168. eCollection 2019 Jun. https://www.ncbi.nlm.nih.gov/pubmed/31183459 Authors’ reply: One-year outcomes for congenital diaphragmatic hernia. Giuliani S1. Author information PMID: 31183459 PMCID: PMC6551414 DOI: 10.1002/bjs5.50168Free PMC Article

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