RESEARCH: “Longitudinal changes in lung size and intrapulmonary artery Doppler during the second half of pregnancy in fetuses with congenital diaphragmatic hernia”

Objective: To evaluate longitudinal changes in lung size and intrapulmonary artery (IPa) Doppler in fetuses with congenital diaphragmatic hernia (CDH) and assess their contribution in predicting neonatal survival.

Methods: The observed/expected lung‐to‐head ratio (O/E‐LHR) and IPa‐Pulsatility Index (PI) and Peak Early Diastolic Reversed Flow (PEDRF) were evaluated in a cohort of left‐sided CDH fetuses managed expectantly during pregnancy. Longitudinal changes were analyzed by multilevel analysis, and their value to predict survival using multiple logistic regression and decision‐tree analysis was assessed.

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