Virtual Ribbons in Honor or Memory of Your Cherub

In honor of CDH Awareness Month, we are honoring all of our CDH babies (survivors and non-survivors) with virtual ribbons to represent the strength and importance of each child born with Congenital Diaphragmatic Hernia. These ribbons will remain posted on our homepage for the month of April. You may add additional ribbons here by making a tax-deductible donation in honor of …


Research: “The Role of FREM2 and FRAS1 in the Development of Congenital Diaphragmatic Hernia”

Congenital diaphragmatic hernia (CDH) has been reported twice in individuals with a clinical diagnosis of Fraser syndrome, a genetic disorder that can be caused by recessive mutations affecting FREM2 and FRAS1. In the extracellular matrix, FREM2 and FRAS1 form a self-stabilizing complex with FREM1, a protein whose deficiency causes sac CDH in humans and mice. By sequencing FREM2 and FRAS1 in a CDH …


Research: “Regeneration of diaphragm with bio-3D cellular patch”

Neonates with congenital diaphragmatic hernia often require surgical defect closure with a patch. Alternatives to native diaphragmatic tissue are critically needed for this paediatric surgery. The clinical efficacy of mesh patches is limited by complications associated with residual foreign material and by hernia recurrence. In this study, we used a novel bio-3D printer method to …

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