Research: Combined extracorporeal membrane oxygenation support and patent ductus arteriosus ligation following surgical correction for congenital diaphragmatic hernia, a case report and literature review

Respir Med Case Rep

. 2025 Apr 22:55:102215.

 doi: 10.1016/j.rmcr.2025.102215. eCollection 2025. https://pubmed.ncbi.nlm.nih.gov/40415759/

Combined extracorporeal membrane oxygenation support and patent ductus arteriosus ligation following surgical correction for congenital diaphragmatic hernia, a case report and literature review

Kun-Yao Hong 1Zhi Zheng 1Yi-Rong Zheng 2Hong Liang 1Liang Gao 1Yu-Cong Lin 1Jin-Xi Huang 2Qiang Chen 2Xin-Zhu Lin 1

Affiliations Expand

Abstract

Our department recently achieved a successful outcome in a case of right-sided CDH. The patient required emergent surgery for right-sided diaphragmatic hernia repair due to severe hypoxemia, followed by urgent bedside venous-arterial ECMO and simultaneous bedside ECMO-assisted patent ductus arteriosus ligation, necessitated by severe hypoxemia and pulmonary hypertension. During the second day on ECMO, the patient developed intracranial hemorrhage, leading to the performance of a lateral ventriculostomy. Fortunately, the patient was successfully weaned off ECMO. This report presents an analysis of the clinical data from this case and shares insights from our experience.

Keywords: Extracorporeal membrane oxygenation (ECMO); Lateral ventriculostomy; Neonate; Patent ductus arteriosus ligation; Right-sided diaphragmatic hernia.

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