Research: Predicting outcomes with compounding comorbidities – Left-sided congenital diaphragmatic hernia complicated by pre-viable premature rupture of the membranes: A case report

Case Rep Womens Health

. 2025 Jan 3:45:e00680.

 doi: 10.1016/j.crwh.2025.e00680. eCollection 2025 Mar. https://pubmed.ncbi.nlm.nih.gov/39867720/

Predicting outcomes with compounding comorbidities – Left-sided congenital diaphragmatic hernia complicated by pre-viable premature rupture of the membranes: A case report

Kate Landau 1George Hardas 1Gordon Thomas 1Maria-Elisabeth Smet 1

Affiliations Expand

Abstract

This case report describes the difficulty in predicting the outcomes for a fetus affected with both left-sided congenital diaphragmatic hernia and second-trimester pre-viable rupture of membranes. Despite the reserved prognosis at the time of diagnosis, a favourable outcome was obtained. The case highlights the relevance of established prognosticators such as the observed/expected lung/head ratio and also underscores the importance of balanced counselling and providing parents with realistic expectations and appropriate support.

Keywords: CDH; Congenital diaphragmatic hernia; PPROM; Pre-viable premature rupture of the membranes.

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