Clin Obstet Gynecol
. 2025 Apr 29.
doi: 10.1097/GRF.0000000000000946. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/40296256/
Prenatal Diagnosis, In Utero Management, and Perinatal Outcomes of Congenital Diaphragmatic Hernia
Felicia V LeMoine 1, Sami Backley, Edgar Hernandez-Andrade, Neha Agarwal, Eric P Bergh, Gustavo Vilchez Lagos, Ramesha Papanna, Sarah Naranjo, Anthony Johnson, Jimmy Espinoza
Affiliations Expand
- PMID: 40296256
- DOI: 10.1097/GRF.0000000000000946
Abstract
Congenital diaphragmatic hernia (CDH) is a complex malformation complicating 0.02% to 0.03% of live births. The etiology of CDH is often multifactorial. Sonographic screening can aid in the detection of ~70% of CDH cases. Sonographic measures, that is, lung-to-head ratio, can also be utilized to predict the severity of fetal/neonatal disease and guide fetal eligibility for prenatal interventions, such as the FETO procedure. The FETO procedure has provided improved overall morbidity and mortality among fetuses with severe left-sided CDH, although limited data on its role in the treatment of right-sided CDH and long-term infant and childhood outcomes are limited.
Keywords: FETO; congenital diaphragmatic hernia; fetoscopic endotracheal occlusion.
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