Semin Fetal Neonatal Med
. 2025 Aug 22:101657.
doi: 10.1016/j.siny.2025.101657. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/40877056/
What is the role of echocardiography in newborns with CDH?
María V Fraga 1, Gabriel Altit 2, Bradley A Yoder 3, Shazia Bhombal 4
Affiliations Expand
- PMID: 40877056
- DOI: 10.1016/j.siny.2025.101657
Abstract
Congenital diaphragmatic hernia (CDH) is associated with high neonatal morbidity and mortality, often due to complex cardiovascular physiology and ventricular dysfunction. Echocardiography is a critical tool for assessing cardiac anatomy, ventricular performance, pulmonary hypertension, and shunt dynamics in both the prenatal and postnatal periods. Early echocardiographic evaluation can identify high-risk physiologic phenotypes and guide targeted interventions, yet optimal timing and frequency remain uncertain. This review outlines the role of fetal and neonatal echocardiography in CDH, highlights view-specific imaging strategies, and discusses key physiologic patterns. While early imaging may inform management, it must be interpreted in context to avoid unnecessary interventions. A targeted, phenotype-driven approach to echocardiography can support individualized care. Further research is needed to establish standardized protocols and determine the impact of echocardiographic timing on outcomes in this vulnerable population.
Keywords: Echocardiography; Newborn; Pulmonary hypertension.
Copyright © 2025. Published by Elsevier Ltd.
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