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cdh research Tag

Congenital diaphragmatic hernia (CDH) is a rare developmental defect of the diaphragm, causing considerable morbidity and mortality1,2. Morphological changes are present from an early developmental stage, consisting of increased muscularization of the pulmonary vessels, rarefication of pulmonary arterioles and capillaries, and a decreased alveolar density3....

This month's foundation spotlight is CDH International. CHERUBS - Congenital Diaphragmatic Hernia Research, Awareness and Support, the support division of CDH International, focuses on promoting research, raising awareness, and providing support services for families of babies born with Congenital Diaphragmatic Hernia. The Kids First Data Resource...

Indications for thoracoscopic versus open approaches to repair congenital diaphragmatic hernia (CDH) are unclear as the variability in defect size, disease severity and patient characteristics pose a challenge. Few studies use a patient and disease-matched comparison of techniques. We aimed to compare the clinical outcomes of open...

Fetal tracheal occlusion (TO) is an emerging surgical therapy in congenital diaphragmatic hernia that improves the fetal lung growth. Different animal models of congenital diaphragmatic hernia and TO present advantages and disadvantages regarding ethical issues, cost, surgical difficulty, size, survival rates, and available genetic tools. We developed a minimally invasive murine transuterine...

We conducted a retrospective cohort study of infants with CDH-associated pulmonary hypertension treated with treprostinil from January 2011 to September 2016. Severity of pulmonary hypertension was assessed by echocardiogram and serum B-type natriuretic peptide (BNP) by using time points before initiation and 24 hours, 1...

Treatment modalities for neonates born with congenital diaphragmatic hernia (CDH) have greatly improved in recent times with a concomitant increase in survival. In 2008, CDH EURO consortium, a collaboration of a large volume of CDH centers in Western Europe, was established with a goal to...