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Congenital Diaphragmatic Hernia

Congenital Diaphragmatic Hernia

Our Mission: CDH International was created to help families of babies born with Congenital Diaphragmatic Hernia by providing support services, promoting research and raising awareness.

Congenital Diaphragmatic Hernia (CDH) is a birth defect that occurs when a baby’s diaphragm (a thin sheet of muscle that separates the abdomen from the chest) fails to fully form, allowing abdominal organs to enter the chest cavity and prevent lung growth.

CDH occurs in approximately 1 in 2500 births, with over 1600 babies diagnosed each year in the United States alone. There is currently no known cause, but studies have suggested that it is likely due to a number of genetic and environmental factors.

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Featured CDHi California Ambassador Francesca Dubroy

Featured CDH International’s California Ambassador is Francesca Dubroy. Francesca is the mom to CDH survivor Francesca. Francesca DuBroy is the manager of Claddagh Paving Corporation, and has been in construction accounting for over 13 years. She the proud mother of two beautiful, strong, and loving kids, her daughter Francesca and her son Jovanni. She has …

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Research: Unintentional longline insertion into the descending aorta in a neonate with left congenital diaphragmatic hernia

Arch Dis Child Fetal Neonatal Ed . 2020 Jul 15;fetalneonatal-2020-319293. doi: 10.1136/archdischild-2020-319293. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/32669359/ Unintentional longline insertion into the descending aorta in a neonate with left congenital diaphragmatic hernia Kerri L Benn 1, Sandeep Shetty 2, Anne Marie Masna 2, Anay M Kulkarni 2 3Affiliations expand PMID: 32669359 DOI: 10.1136/archdischild-2020-319293 No abstract available

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Research: Successful lung response after surgical repair in an infant with right-sided congenital diaphragmatic hernia

Case Reports Radiol Case Rep . 2020 Jul 3;15(9):1502-1505. doi: 10.1016/j.radcr.2020.06.020. eCollection 2020 Sep. https://pubmed.ncbi.nlm.nih.gov/32670449/ Successful lung response after surgical repair in an infant with right-sided congenital diaphragmatic hernia Giorgia Gasparroni 1, Marika Perrotta 1, Valentina Chiavaroli 2, Altea Petrucci 2, Simona Di Credico 2, Paola Cicioni 2, Angelika Mohn 1, Gabriele Lisi 3, Pierluigi Lelli Chiesa 3, Susanna Di Valerio 2Affiliations expand PMID: 32670449 PMCID: PMC7339008 DOI: 10.1016/j.radcr.2020.06.020 Free PMC article Abstract Congenital diaphragmatic hernia is a rare condition associated with …

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Research: Ten years of the neonatal respiratory extracorporeal membrane oxygenation program in an Argentinian public hospital

Arch Argent Pediatr . 2020 Aug;118(4):258-264. doi: 10.5546/aap.2020.eng.258. https://pubmed.ncbi.nlm.nih.gov/32677787/ Ten years of the neonatal respiratory extracorporeal membrane oxygenation program in an Argentinian public hospital [Article in En, Spanish]Gisela L Salas 1, María S Arbio 2, Sonia B Rodas 2, Eduardo D Domínguez 2, Gustavo S Goldsmit 2, Diana M Fariña 2Affiliations expand PMID: 32677787 DOI: 10.5546/aap.2020.eng.258 Free article Abstract in En , Spanish Introduction: Extracorporeal membrane oxygenation (ECMO) is a highly invasive rescue treatment for critically-ill …

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Research: Short bowel syndrome as an unusual complication of strangulated congenital diaphragmatic hernia: Case report

Case Reports Int J Surg Case Rep . 2020 Jul 10;73:125-129. doi: 10.1016/j.ijscr.2020.06.103. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/32682322/ Short bowel syndrome as an unusual complication of strangulated congenital diaphragmatic hernia: Case report Reema AlSadhan 1, Abdulaziz K Alaraifi 2, Magdy Abdulatif 3Affiliations expand PMID: 32682322 PMCID: PMC7365962 DOI: 10.1016/j.ijscr.2020.06.103 Free PMC article Abstract Introduction: Strangulation is a rare complication of congenital diaphragmatic hernia (CDH). There are few cases in …

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Research: Melatonin ameliorates necrotizing enterocolitis by preventing Th17/Treg imbalance through activation of the AMPK/SIRT1 pathway

Theranostics . 2020 Jun 19;10(17):7730-7746. doi: 10.7150/thno.45862. eCollection 2020. https://pubmed.ncbi.nlm.nih.gov/32685016/ Melatonin ameliorates necrotizing enterocolitis by preventing Th17/Treg imbalance through activation of the AMPK/SIRT1 pathway Fei Ma 1 2, Hu Hao 1, Xiaoyan Gao 3, Yao Cai 1, Jialiang Zhou 4, Puping Liang 5, Junjian Lv 6, Qiuming He 6, Congcong Shi 1, Dandan Hu 6, Bowei Chen 7, Lixin Zhu 2, Xin Xiao 1, Sitao Li 1Affiliations expand PMID: 32685016 PMCID: PMC7359097 DOI: 10.7150/thno.45862 Free PMC article Abstract Necrotizing enterocolitis (NEC) is a severe gastrointestinal disease affecting premature infants. Mounting …

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Research: Postnatally diagnosed coexisting congenital diaphragmatic hernia with pulmonary sequestration: a report of two cases

Obstet Gynecol Sci . 2020 Jul;63(4):529-533. doi: 10.5468/ogs.20052. Epub 2020 Jul 8. https://pubmed.ncbi.nlm.nih.gov/32689778/ Postnatally diagnosed coexisting congenital diaphragmatic hernia with pulmonary sequestration: a report of two cases Hyun Mi Kim 1 2, Ja Hyun Hwang 1 2, Mi Ju Kim 1 3, Hyun-Hwa Cha 1 2, Won Joon Seong 1 2Affiliations expand PMID: 32689778 DOI: 10.5468/ogs.20052 Free article Abstract While the associations between pulmonary sequestration (PS) and congenital diaphragmatic hernia (CDH) are known, CDH may …

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Research: Prevalence and risk factors for congenital diaphragmatic hernia: A global view

Review J Pediatr Surg . 2020 Jun 20;S0022-3468(20)30442-5. doi: 10.1016/j.jpedsurg.2020.06.022. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/32690291/ Prevalence and risk factors for congenital diaphragmatic hernia: A global view Monica Paoletti 1, Gabriele Raffler 1, Maria Sole Gaffi 1, Lina Antounians 1, Giuseppe Lauriti 2, Augusto Zani 3Affiliations expand PMID: 32690291 DOI: 10.1016/j.jpedsurg.2020.06.022 Abstract Purpose: To determine the global prevalence for congenital diaphragmatic hernia (CDH) and identify CDH-related risk factors. Methods: Using a defined strategy, a systematic review …

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Research: Expanding the phenotypic spectrum associated with DPF2: A new case report

Case Reports Am J Med Genet A . 2019 Aug;179(8):1637-1641. doi: 10.1002/ajmg.a.61262. Epub 2019 Jun 17. https://pubmed.ncbi.nlm.nih.gov/31207137/ Expanding the phenotypic spectrum associated with DPF2: A new case report Karen M Knapp 1, Gemma Poke 2, Danielle Jenkins 1, Werner Truter 3, Louise S Bicknell 1Affiliations expand PMID: 31207137 DOI: 10.1002/ajmg.a.61262 Abstract Coffin-Siris syndrome (CSS) is a clinically and genetically heterogeneous developmental disorder, linked to disruption of the BAF chromatin-remodeling complex. Recently, …

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Research: Neonatal platelet count trends during inhaled nitric oxide therapy

Br J Haematol . 2020 Feb;188(3):e28-e30. doi: 10.1111/bjh.16301. Epub 2019 Dec 15. https://pubmed.ncbi.nlm.nih.gov/31840227/ Neonatal platelet count trends during inhaled nitric oxide therapy Christopher S Thom 1, Matthew Devine 1, Stacey Kleinman 1, Erik A Jensen 1, Michele P Lambert 2, Michael A Padula 1Affiliations expand PMID: 31840227 PMCID: PMC6982552 (available on 2021-02-01) DOI: 10.1111/bjh.16301 Free PMC articleNo abstract available

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Research: Which Is the Better Approach for Late-Presenting Congenital Diaphragmatic Hernia: Laparoscopic or Thoracoscopic? A Single Institution’s Experience of more than 10 Years

J Laparoendosc Adv Surg Tech A . 2020 Jul 21. doi: 10.1089/lap.2019.0162. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/32716256/ Which Is the Better Approach for Late-Presenting Congenital Diaphragmatic Hernia: Laparoscopic or Thoracoscopic? A Single Institution’s Experience of more than 10 Years Satoshi Obata 1, Ryota Souzaki 1, Atsuhisa Fukuta 1, Genshiro Esumi 1, Kouji Nagata 1, Toshiharu Matsuura 1, Satoshi Ieiri 2, Tomoaki Taguchi 1Affiliations expand PMID: 32716256 DOI: 10.1089/lap.2019.0162 Abstract Aim: We evaluated a series of late-presenting congenital …

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