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Congenital Diaphragmatic Hernia

Congenital Diaphragmatic Hernia

Our Mission: CDH International was created to help families of babies born with Congenital Diaphragmatic Hernia by providing support services, promoting research and raising awareness.

Congenital Diaphragmatic Hernia (CDH) is a birth defect that occurs when a baby’s diaphragm (a thin sheet of muscle that separates the abdomen from the chest) fails to fully form, allowing abdominal organs to enter the chest cavity and prevent lung growth.

CDH occurs in approximately 1 in 2500 births, with over 1600 babies diagnosed each year in the United States alone. There is currently no known cause, but studies have suggested that it is likely due to a number of genetic and environmental factors.

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Research: Neurally adjusted ventilatory assist in neonates with congenital diaphragmatic hernia

J Perinatol . 2021 Jun 10;1-6. doi: 10.1038/s41372-021-01098-3. Online ahead of print . https://pubmed.ncbi.nlm.nih.gov/34112964/ Neurally adjusted ventilatory assist in neonates with congenital diaphragmatic hernia Yonatan Kurland 1, Kamal Gurung 2, Eugenia K Pallotto 3, Winston Manimtim 2, Keith Feldman 4, Vincent S Staggs 5, William Truog 2Affiliations expand PMID: 34112964 PMCID: PMC8191439 DOI: 10.1038/s41372-021-01098-3 Free PMC article Abstract Objective: To measure short-term outcomes of neonates with congenital diaphragmatic hernia (CDH) while on Neurally Adjusted Ventilator Assist …

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Research: Role of Imaging in Obstetric Interventions: Criteria, Considerations, and Complications

Radiographics . 2021 Jun 11;200163. doi: 10.1148/rg.2021200163. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/34115536/ Role of Imaging in Obstetric Interventions: Criteria, Considerations, and Complications Priyanka Jha 1, Vickie A Feldstein 1, Margarita V Revzin 1, Douglas S Katz 1, Mariam Moshiri 1Affiliations expand PMID: 34115536 DOI: 10.1148/rg.2021200163 Abstract US has an established role in the prenatal detection of congenital and developmental disorders. Many pregnant women undergo US at 18-20 weeks of gestation …

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Research: Factors and Growth Trends Associated with the Need for Gastrostomy Tube in Neonates with Congenital Diaphragmatic Hernia

J Pediatr Gastroenterol Nutr . 2021 Jun 10. doi: 10.1097/MPG.0000000000003203. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/34117194/ Factors and Growth Trends Associated with the Need for Gastrostomy Tube in Neonates with Congenital Diaphragmatic Hernia Marisa E Schwab 1, Shannon Burke, Mary Kate Klarich, Lan T VuAffiliations expand PMID: 34117194 DOI: 10.1097/MPG.0000000000003203 Abstract Objectives: A third of infants with congenital diaphragmatic hernia (CDH) require a gastrostomy tube (GT) for …

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Research: Risk factors for acute kidney injury in neonates with congenital diaphragmatic hernia

J Perinatol . 2021 Jun 12;1-9. doi: 10.1038/s41372-021-01119-1. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/34120147/ Risk factors for acute kidney injury in neonates with congenital diaphragmatic hernia Brianna M Liberio 1, John T Brinton 2, Katja M Gist 3, Danielle E Soranno 4, Megan J Kirkley 5 6, Jason Gien 5Affiliations expand PMID: 34120147 PMCID: PMC8196921 DOI: 10.1038/s41372-021-01119-1 Free PMC article Abstract Objective: To examine incidence of acute kidney injury (AKI), antenatal and postnatal predictors, and impact …

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Research: Parental risk factors for congenital diaphragmatic hernia – a large German case-control study

BMC Pediatr . 2021 Jun 14;21(1):278. doi: 10.1186/s12887-021-02748-3. https://pubmed.ncbi.nlm.nih.gov/34126946/ Parental risk factors for congenital diaphragmatic hernia – a large German case-control study Felicitas Schulz 1 2, Ekkehart Jenetzky 3 4, Nadine Zwink 3, Charlotte Bendixen 5, Florian Kipfmueller 6, Neysan Rafat 7, Andreas Heydweiller 8, Lucas Wessel 9, Heiko Reutter 6 10, Andreas Mueller 6, Thomas Schaible 7Affiliations expand PMID: 34126946 PMCID: PMC8201820 DOI: 10.1186/s12887-021-02748-3 Free PMC article Abstract Background: Evidence for periconceptional or prenatal environmental risk factors for the development of congenital diaphragmatic hernia (CDH) …

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Research: A prompt diagnosis of late-onset congenital diaphragmatic hernia with Point of Care Ultrasound (POCUS) in a Pediatric Emergency Department

Pediatr Neonatol . 2021 May 29;S1875-9572(21)00089-9. doi: 10.1016/j.pedneo.2021.05.010. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/34127399/ A prompt diagnosis of late-onset congenital diaphragmatic hernia with Point of Care Ultrasound (POCUS) in a Pediatric Emergency Department Angelo Giovanni Delmonaco 1, Marianna Genisio 2, Federico Scottoni 3, Ludovica Fiore 4, Irene Raffaldi 5, Emanuela Garrone 5, Fabrizio Gennari 3, Antonio Francesco Urbino 5Affiliations expand PMID: 34127399 DOI: 10.1016/j.pedneo.2021.05.010 No abstract available

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Research: Optimal timing of delivery for pregnancies with prenatally diagnosed congenital diaphragmatic hernia: a propensity-score analysis using the inverse probability of treatment weighting

J Perinatol . 2021 Jun 14. doi: 10.1038/s41372-021-01118-2. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/34127793/ Optimal timing of delivery for pregnancies with prenatally diagnosed congenital diaphragmatic hernia: a propensity-score analysis using the inverse probability of treatment weighting Yoko Kawanishi 1, Masayuki Endo 1 2, Makoto Fujii 3, Tatsuo Masuda 3, Noriaki Usui 4, Kouji Nagata 5, Keita Terui 6, Masahiro Hayakawa 7, Shoichiro Amari 8, Kouji Masumoto 9, Tadaharu Okazaki 10, Noboru Inamura 11, Naoto Urushihara 12, Katsuaki Toyoshima 13, Keiichi Uchida 14, Taizo Furukawa 15, Manabu Okawada 16, Akiko Yokoi 17, Tomoaki Taguchi 5, Hiroomi Okuyama 18Affiliations expand PMID: 34127793 DOI: 10.1038/s41372-021-01118-2 …

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Research: Impact of fetal endoscopic tracheal occlusion in fetuses with congenital diaphragmatic hernia and moderate lung hypoplasia

Prenat Diagn . 2021 Jun 15. doi: 10.1002/pd.5988. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/34132402/ Impact of fetal endoscopic tracheal occlusion in fetuses with congenital diaphragmatic hernia and moderate lung hypoplasia Rogelio Cruz-Martínez 1 2, Sherif Shazly 1, Miguel Martínez-Rodríguez 1, Alma Gámez-Varela 1, Jonahtan Luna-García 1, Israel Juárez-Martínez 1, Hugo López-Briones 1, Fausto Coronel-Cruz 3, Rosa Villalobos-Gómez 1, Daniel Ibarra-Rios 4, Ricardo Ordorica-Flores 5, Jaime Nieto-Zermeño 5Affiliations expand PMID: 34132402 DOI: 10.1002/pd.5988 Abstract Objective: To assess the effect of Fetal Endoscopic Tracheal Occlusion (FETO) on neonatal survival …

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Research: A systematic review and meta-analysis of surgical morbidity of primary versus patch repaired congenital diaphragmatic hernia patients

Sci Rep . 2021 Jun 16;11(1):12661. doi: 10.1038/s41598-021-91908-7. https://pubmed.ncbi.nlm.nih.gov/34135386/ A systematic review and meta-analysis of surgical morbidity of primary versus patch repaired congenital diaphragmatic hernia patients Kim Heiwegen 1, Ivo de Blaauw 2, Sanne M B I Botden 2Affiliations expand PMID: 34135386 DOI: 10.1038/s41598-021-91908-7 Abstract Large studies comparing the surgical outcome of primary versus patch repair in congenital diaphragmatic hernia (CDH) patients are rare. This …

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