J Perinatol
. 2023 Dec 9.
doi: 10.1038/s41372-023-01845-8. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/38071241/
Oxygen saturation index: an adjunct for oxygenation index in congenital diaphragmatic hernia
Srirupa Hari Gopal 1, Kelly F Martinek 2, Amanda Holmes 2, Joseph L Hagan 2, Caraciolo J Fernandes 2
Affiliations expand
- PMID: 38071241
- DOI: 10.1038/s41372-023-01845-8
Abstract
Objective: Our objective was to investigate the correlation of Oxygen Saturation Index (OSI) with Oxygenation Index (OI) and determine OSImax values that could predict need for ECMO and death in Congenital Diaphragmatic Hernia (CDH).
Study design: This is a retrospective cohort study of infants with CDH admitted to a tertiary level VI NICU. Pearson’s correlation coefficient and simple linear regression analysis were used to investigate the OSI: OI correlation, and logistic regression analysis to investigate OSImax values that predicted need for ECMO and death.
Results: Among the 180 infants, OSImax value of >13 at 6 h of life (HOL) best predicted need for ECMO and death. There was a strong correlation between OSI: OI paired values (r = 0.876, p < 0.001). The linear regression equation was OI = -2.4 + 2.4(OSI).
Conclusion: OSI could be used as a valuable adjunct to OI in the clinical management of newborn infants with CDH.
© 2023. The Author(s), under exclusive licence to Springer Nature America, Inc.
