Semin Pediatr Surg
. 2024 Jul 3;33(4):151438.
doi: 10.1016/j.sempedsurg.2024.151438. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/39018716/
Cardiac function in congenital diaphragmatic hernia
Gabriel Altit 1, Anie Lapointe 2, Florian Kipfmueller 3, Neil Patel 4
Affiliations expand
- PMID: 39018716
- DOI: 10.1016/j.sempedsurg.2024.151438
Abstract
Cardiac function is known to play critical role in the pathophysiological progression and ultimate clinical outcome of patients with congenital diaphragmatic hernia (CDH). While often anatomically normal, the fetal and neonatal heart in CDH can suffer from both right and left ventricular dysfunction. Here we explore the abnormal fetal heart, early postnatal right and left ventricular dysfunction, the interplay between cardiac dysfunction and pulmonary hypertension, evaluation and echocardiographic assessment of the heart, and therapeutic strategies for managing and supporting the pathophysiologic heart and CDH. Further, we take a common clinical scenario and provide clinically relevant guidance for the diagnosis and management of this complex process.
Keywords: Cardiac; Congenital diaphragmatic hernia; Echocardiography; Fetal; Hemodynamic; Neonatal; Pulmonary hypertension; Ventricular.
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