Am J Perinatol. 2020 Mar 13. doi: 10.1055/s-0040-1705136. [Epub ahead of print] https://www.ncbi.nlm.nih.gov/pubmed/32168528
Growth from Birth to 30 months for Infants Born with Congenital Gastrointestinal Anomalies and Disorders.
Strobel KM1, Purdy I1, Romero T2, Calkins KL1.
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Abstract
OBJECTIVE:
This study aimed to investigate growth among neonates with gastrointestinal disorders.
STUDY DESIGN:
Inclusion criteria included neonates with gastroschisis, omphalocele, intestinal atresia, tracheoesophageal fistula, Hirschsprung’s disease, malabsorption disorders, congenital diaphragmatic hernia, and imperforate anus born between 2010 and 2018. Anthropometrics were collected for the first 30 months, and a subgroup analysis was performed for gastroschisis infants.
RESULTS:
In 61 subjects, 13% developed severe growth failure within the first month. One-, four-, and nine-month weight and length z-scores were less than birth weight in all infants (p < 0.05). In infants with gastroschisis, a similar pattern was observed for weight z-scores only (p < 0.05). From birth to 15 months, head circumference z-score increased over time in all infants (p = 0.001), while in gastroschisis infants, weight, length, and head circumference z-scores increased over time (p < 0.05).
CONCLUSION:
In a cohort of infants with gastrointestinal disorders, growth failure was followed by catch-up growth.
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.PMID: 32168528 DOI: 10.1055/s-0040-1705136
