Front Pediatr

. 2023 Jun 27;11:1158885.

 doi: 10.3389/fped.2023.1158885. eCollection 2023. https://pubmed.ncbi.nlm.nih.gov/37441572/

Successful extracorporeal membrane oxygenation for postoperative cardiopulmonary failure in newborns with congenital diaphragmatic hernia: case reports and literature reviews

Song-Ming Hong ¹, Xiu-Hua Chen ¹, Si-Jia Zhou ¹, Jun-Jie Hong ¹, Yi-Rong Zheng ¹, Qiang Chen ¹, Jin-Xi Huang ¹

Affiliations expand

• PMID: 37441572
• PMCID: PMC10333486
• DOI: 10.3389/fped.2023.1158885

Free PMC article

Abstract

Introduction: Congenital diaphragmatic hernia (CDH) is a structural defect caused by inadequate fusion of the pleuroperitoneal membrane that forms the diaphragm, allowing peritoneal viscera to protrude into the pleural cavity. Up to 30% of newborns with CDH require extracorporeal membrane oxygenation (ECMO) support. As with all interventions, the risks and benefits of ECMO must be carefully considered in these patients. Cardiopulmonary function has been shown to worsen rather than improve after surgical CDH repair. Even after a detailed perioperative assessment, sudden cardiopulmonary failure after surgery is dangerous and requires timely and effective treatments.

Method: Three cases of cardiopulmonary failure after surgical CDH treatment in newborns have been reported. ECMO support was needed for these three patients and was successfully discontinued. We report our treatment experience.

Conclusion: ECMO is feasible for the treatment of postoperative cardiopulmonary failure in newborns with CDH.

Keywords: cardiopulmonary failure; congenital diaphragmatic hernia; extracorporeal membrane oxygenation; newborn; postoperative.

© 2023 Hong, Chen, Zhou, Hong, Zheng, Chen and Huang.