J Pediatr

. 2023 May 16;113490.

 doi: 10.1016/j.jpeds.2023.113490. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/37201678/

Failure to Normalize Biventricular Function is Associated with Extracorporeal Membrane Oxygenation Use in Neonates with Congenital Diaphragmatic Hernia

Lisa S Le ¹, John P Kinsella ², Jason Gien ², Benjamin Frank ³

Affiliations expand

• PMID: 37201678
• DOI: 10.1016/j.jpeds.2023.113490

Abstract

We examined post-natal echocardiograms for 62 congenital diaphragmatic hernia (CDH) infants born from 2014 through 2020. Left and right ventricular dysfunction on D0 were sensitive while persistent dysfunction on D2 was specific for extracorporeal membrane oxygenation (ECMO) requirement. Biventricular dysfunction had the strongest association with ECMO. Serial echocardiography may inform prognosis in CDH.

Keywords: ECMO; Left ventricular dysfunction; pulmonary hypertension; right ventricular dysfunction.

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