Research: Fetal tracheal occlusion for congenital diaphragmatic hernia

Semin Perinatol. 2019 Jul 30:151164. doi: 10.1053/j.semperi.2019.07.003. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31451196

Fetal tracheal occlusion for congenital diaphragmatic hernia.

Tsao K1Johnson A2.

Author information

1Departments of Pediatric Surgery and Obstetrics, Gynecology & Reproductive Sciences, McGovern Medical School at the University of Texas Health Science Center at Houston and Children’s Memorial Hermann Hospital, Houston, TX, United States. Electronic address: Kuojen.tsao@uth.tmc.edu.2Departments Obstetrics, Gynecology & Reproductive Sciences and Pediatric Surgery, Division of Maternal-Fetal Medicine, McGovern Medical School at the University of Texas Health Science Center at Houston and Children’s Memorial Hermann Hospital, Houston, TX, United States.

Abstract

Congenital diaphragmatic hernia (CDH) remains one of the most elusive birth defects to treat. Despite greater knowledge of disease and advances in technology, approximately one-third of CDH children born today still die. Consequently, clinicians and researchers have struggled to find the optimal treatment strategies for CDH. Without further innovations in postnatal treatment, many have focused an antenatal approach to improve pulmonary function. Fetoscopic Endoluminal Tracheal Occlusion (FETO) for CDH has evolved to the bedside after decades of research. While still under clinical investigation, FETO remains a promising adjunct to the treatment of CDH.

Copyright © 2019 Elsevier Inc. All rights reserved.

KEYWORDS:

Congenital diaphragmatic hernia; FETO; Fetal surgery; Tracheal occlusionPMID: 31451196 DOI: 10.1053/j.semperi.2019.07.003

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