Pediatr Surg Int
. 2022 Jun 7;1-11.
doi: 10.1007/s00383-022-05136-9. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/35670846/
Impact of the COVID-19 pandemic on congenital diaphragmatic hernia patients: a single-center retrospective study
Yun-Long Zhao 1, Ying Wang 2, Chao Liu 2, Yu-Lin Jiang 3, Yan-Dong Wei 2, Hua Meng 4, Shan Jian 5, Xi-Ting Zhu 6, Li-Jian Pei 7, Xiao-Chen Bai 8, Feng Feng 9, Yan Lv 3, Xi-Ya Zhou 3, Qing-Wei Qi 3, Jing-Na Li 2, Wei Ji 10, Li-Shuang Ma 11
Free PMC article
Purpose: To investigate the impact of COVID-19 on the treatment of children with congenital diaphragmatic hernia (CDH).
Methods: We retrospectively collected and compared the data of patients with CDH admitted between January 1, 2020 and December 31, 2021(study group) with the CDH patients admitted before the pandemic between January 1, 2018 and December 31, 2019 (control group).
Results: During the pandemic, 41 patients with CDH diagnosed prenatally were transferred to our hospital, and 40 underwent surgical repair. The number of patients treated in our hospital increased by 24.2% compared with the 33 patients before the pandemic. During the pandemic, the overall survival rate, postoperative survival rate and recurrence rate were 85.4%, 87.5% and 7.3%, respectively, and there were no significant differences compared with the control group (75.8%, 83.3% and 9.1%, respectively). The average length of hospital stay in patients admitted during the pandemic was longer than that in the control group (31 days vs. 16 days, P < 0.001), and the incidence of nosocomial infection was higher than that in the control group (19.5% vs. 3%, P = 0.037).
Conclusions: CDH patients confirmed to be SARS-CoV-2 infection-free can receive routine treatment. Our data indicate that the implementation of protective measures during the COVID-19 pandemic, along with appropriate screening and case evaluation, do not have a negative impact on the prognosis of children.
Keywords: Clinical management; Congenital diaphragmatic hernia; Neonates; Public health emergency; Surgery.
© 2022. The Author(s).