J Pediatr Surg

. 2020 Oct 1;S0022-3468(20)30667-9. doi: 10.1016/j.jpedsurg.2020.09.018. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/33268050/

One-year outcomes of congenital diaphragmatic hernia repair: Factors associated with recurrence and complications

Alessia C Cioci ¹, Eva M Urrechaga ¹, Joshua Parreco ², Lindsay F Remer ³, Maiya Cowan ³, Eduardo A Perez ¹, Juan E Sola ¹, Chad M Thorson ⁴Affiliations expand

• PMID: 33268050
• DOI: 10.1016/j.jpedsurg.2020.09.018

Abstract

Purpose: Congenital diaphragmatic hernia (CDH) is a congenital anomaly associated with lifelong multisystem morbidity. This study sought to identify factors contributing to hospital readmission after CDH repair.

Methods: The Nationwide Readmissions Database from 2010 to 2014 was used to identify patients with CDH who underwent surgical repair. Primary outcomes included all cause readmission at 30-days and 1 year and readmission for hernia recurrence. Patient and hospital factors were compared using chi-squared analysis.

Results: Five hundred eleven patients were identified with neonatal CDH. All repairs were performed at teaching hospitals via laparotomy in 59% (n = 303), thoracotomy in 36% (n = 183), and minimally invasive (MIS) repair in 5% (n = 25). The readmission rate within 30-days was 32% (n = 163), and 97% (n = 495) within 1 year. The most common conditions surrounding readmission were for gastroesophageal reflux (20%), CDH recurrence (17%), and surgery for gastrostomy tube and/or fundoplication (16%). Recurrence was significantly higher after MIS repair (48%) compared to those with open repair via either approach (16%), p < 0.001.

Conclusions: This is the first study to evaluate nationwide readmissions in newborns with CDH. Readmission is commonly due to CDH recurrence and reflux-associated complications. The recurrence rate is higher than previously reported and is more common after MIS and repair via thoracotomy.

Level of evidence: Level III treatment study.

Keywords: Congenital diaphragmatic hernia; Hernia recurrence; Minimally invasive surgery.

Copyright © 2020. Published by Elsevier Inc.