Research: Radiographic, MRI, and CT findings in a young dog with Becker-like muscular dystrophy

Vet Radiol Ultrasound

. 2023 Mar;64(2):E19-E22.

 doi: 10.1111/vru.13200. Epub 2022 Dec 22. https://pubmed.ncbi.nlm.nih.gov/36550687/

Radiographic, MRI, and CT findings in a young dog with Becker-like muscular dystrophy

Giulia Costanzo 1Sergio Minei 1Eric Zini 1 2 3Margherita Gracis 1Giuseppe Lacava 1

Affiliations expand

Abstract

An 8-month-old, male, crossbreed dog was presented for macroglossia, reduced mandibular extension, ptyalism, dysphagia, and regurgitation. Serum creatine kinase and aspartate aminotransferase activity were markedly increased. Thoracic radiographs showed an axial gastro-esophageal hiatal hernia, diaphragmatic thickening, and asymmetry. Magnetic resonance imaging of the head showed a severely enlarged tongue, symmetric increase in size of the geniohyoid and mylohyoid muscles, and diffuse masticatory hypomyotrophy. Whole-body CT ruled out other musculoskeletal abnormalities and further characterized the radiographic and MRI findings. Muscular histopathology was consistent with Becker muscular dystrophy.

Keywords: Canine; dystrophin; gene; masticatory myopathy; muscular biopsy.

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