Pediatr Surg Int

. 2023 Jan 16;39(1):82.

 doi: 10.1007/s00383-022-05312-x. https://pubmed.ncbi.nlm.nih.gov/36645513/

Thoracoscopic vs open repair of congenital diaphragmatic hernia after extracorporeal membrane oxygenation: a comparison of intra-operative data

Annita Budzanowski ¹, Stavros Loukogeorgakis ^1 2, Dhanya Mullassery ¹, Simon Blackburn ¹, Joe Curry ¹, Ioannis Ioannou ³, Usman Ali ³, Kate Cross ¹, Stefano Giuliani ¹, Paolo De Coppi ^4 5

Affiliations expand

• PMID: 36645513
• PMCID: PMC9842545
• DOI: 10.1007/s00383-022-05312-x

Free PMC article

Abstract

Purpose: ECMO is an escalation treatment for hypoxic respiratory failure in patients with CDH. Open repair has been advocated after ECMO indicating that physiological changes associated to thoracoscopic repair were not well tolerated.

Methods: We have performed a retrospective review of all patients who underwent ECMO prior CDH repair over a 7 year period (2015-2021). Outcome measures were intra-operative Ph, PCO₂, PO₂ and FiO₂ at 30 min, 1 h 30 min, and 2 h 30 min of surgery, operative time and recurrence rate. Data are shown in median (range).

Results: Eleven patients required ECMO prior CDH repair. Six of eleven (55%) were done thoracoscopically (Group A) and five of eleven (45%) via laparotomy (Group B). Two of six (33%) patients (Group A) were converted to a laparotomy, one of six (16%) patient developed a recurrence, and there was no recurrence in Group B. Two of five (40%) patients died within the first 60 days of life, whilst there was no death in Group A. Intra-operative values are shown below.

Conclusion: Whilst this is a preliminary report of a limited number of patients, there is no obvious difference of intra-operative blood gas parameters during surgical repair in patients after ECMO. Thoracoscopic CDH repair may be considered in patients after ECMO.

Keywords: CDH; ECMO; Minimal invasive surgery; Neonates.

© 2023. The Author(s).