J Perinatol. 2019 Oct 17. doi: 10.1038/s41372-019-0523-6. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/31624324
Survival trends and outcomes among preterm infants with congenital diaphragmatic hernia.
Peluso AM1, Othman HF2, Elsamny EM2, Sammour I2, Yeaney NK2, Aly H2.
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Abstract
OBJECTIVE:
The objective of this study was to use current national data to evaluate the characteristics and survival trends of preterm infants born with CDH from 2004 to 2014.
STUDY DESIGN:
Data was queried from the National Inpatient Sample (NIS) and KID database from 2004 to 2014. Infants were included if diagnosed with CDH by ICD-9 coding and gestational age <37 weeks. Descriptive statistics, chi-square, and trend analysis were completed.
RESULTS:
We identified 2356 infants born prematurely with CDH. The overall survival rate was 49%. The survival range is 21.2-62.3% for gestational age <26 weeks to 35-36 weeks, respectively. Total mortality was 1183; of them, 1052 (89%) were not repaired and 363 (30.7%) did not receive mechanical ventilation. Surgical repair occurred in 55.1% of infants.
CONCLUSIONS:
Preterm infants have lower survival compared with term infants. Survival rates decrease with lower gestational age and have improved over time.PMID: 31624324 DOI: 10.1038/s41372-019-0523-6
