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Research: Survival trends and outcomes among preterm infants with congenital diaphragmatic hernia.

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Research: Survival trends and outcomes among preterm infants with congenital diaphragmatic hernia.

J Perinatol. 2019 Oct 17. doi: 10.1038/s41372-019-0523-6. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31624324

Survival trends and outcomes among preterm infants with congenital diaphragmatic hernia.

Peluso AM1Othman HF2Elsamny EM2Sammour I2Yeaney NK2Aly H2.

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Abstract

OBJECTIVE:

The objective of this study was to use current national data to evaluate the characteristics and survival trends of preterm infants born with CDH from 2004 to 2014.

STUDY DESIGN:

Data was queried from the National Inpatient Sample (NIS) and KID database from 2004 to 2014. Infants were included if diagnosed with CDH by ICD-9 coding and gestational age <37 weeks. Descriptive statistics, chi-square, and trend analysis were completed.

RESULTS:

We identified 2356 infants born prematurely with CDH. The overall survival rate was 49%. The survival range is 21.2-62.3% for gestational age <26 weeks to 35-36 weeks, respectively. Total mortality was 1183; of them, 1052 (89%) were not repaired and 363 (30.7%) did not receive mechanical ventilation. Surgical repair occurred in 55.1% of infants.

CONCLUSIONS:

Preterm infants have lower survival compared with term infants. Survival rates decrease with lower gestational age and have improved over time.PMID: 31624324 DOI: 10.1038/s41372-019-0523-6

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