J Intensive Care Med
. 2023 Nov 6:8850666231212874.
doi: 10.1177/08850666231212874. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/37933125/
Update on Management and Outcomes of Congenital Diaphragmatic Hernia
K Taylor Wild 1, Holly L Hedrick 2 3, Anne M Ades 1, Maria V Fraga 1, Catherine M Avitabile 4, Juliana S Gebb 2, Edward R Oliver 5, Kristen Coletti 1, Erin M Kesler 3, K Taylor Van Hoose 3, Howard B Panitch 6, Sandy Johng 1, Renee P Ebbert 3, Lisa M Herkert 3, Casey Hoffman 7, Deanna Ruble 2, Sabrina Flohr 2, Tom Reynolds 2, Melissa Duran 3, Audrey Foster 8, Rebecca S Isserman 9, Emily A Partridge 2 3, Natalie E Rintoul 1
- PMID: 37933125
- DOI: 10.1177/08850666231212874
Infants with congenital diaphragmatic hernia (CDH) benefit from comprehensive multidisciplinary teams that have experience in caring for the unique and complex issues associated with CDH. Despite prenatal referral to specialized high-volume centers, advanced ventilation strategies and pulmonary hypertension management, and extracorporeal membrane oxygenation, mortality and morbidity remain high. These infants have unique and complex issues that begin in fetal and infant life, but persist through adulthood. Here we will review the literature and share our clinical care pathway for neonatal care and follow up. While many advances have occurred in the past few decades, our work is just beginning to continue to improve the mortality, but also importantly the morbidity of CDH.
Keywords: congenital diaphragmatic hernia; extracorporeal membrane oxygenation; pulmonary hypertension.