RESEARCH: “Fetal endoscopic tracheal occlusion reduces pulmonary hypertension in severe congenital diaphragmatic hernia.”

OBJECTIVE: Fetal endoscopic tracheal occlusion (FETO) is associated with increased perinatal survival and reduced need for Extracorporeal Membrane Oxygenation (ECMO) among fetuses with severe congenital diaphragmatic hernia (CDH). This study evaluates the impact of FETO on the resolution of pulmonary hypertension (PH) in fetuses with isolated CDH.

METHODS: All fetuses evaluated for CDH between January 2004 and July 2017 at a single institution were included. CDH cases were retrospectively reclassified by prenatal MRI severity indices, (observed to expected total lung volume and percent liver herniation) into mild, moderate, and severe groups.

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